| Brachial artery occlusion secondary to hypereosinophilic syndrome. | |
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MedLine Citation:
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PMID: 16242572 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypereosinophilic syndrome (HES) is characterized by an overproduction of eosinophils that leads to organ damage. Although most cases of HES frequently affect the lungs, heart, and gastrointestinal tract, there are a few reported cases of peripheral vascular involvement. We report a case of a patient with a history of colonic HES who presented with idiopathic occlusion of the brachial artery. A 28-year-old woman with a recent history of eosinophilic colitis presented with a several-week history of left hand pain, pallor, and paresthesias. Her hand was cool, without palpable pulses. Her eosinophilia count was 38%. An arteriogram documented a left brachial artery occlusion and diffuse left arm vasospasm. A brachial-to-brachial bypass was performed. Postoperatively, there was extensive vasospasm of her distal upper extremity arteries, which was treated with calcium-channel blockers and steroids. Her symptoms resolved and she has been asymptomatic for 9 months. The segment of occluded artery was found to contain many eosinophils on histologic examination. HES of the arterial system is an exceedingly rare cause of occlusion. Our patient presented with eosinophilia, arterial vasospasm with subsequent occlusion, and the presence of eosinophilic infiltration on the pathologic specimen. These data, combined with the patient's previous history, demonstrate that the patient's occlusion may have been secondary to HES. |
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Authors:
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Todd A Ponsky; Fredrick Brody; Joseph Giordano; Ryan Garcia; David Kardon; Arnold Schwartz |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter Volume: 42 ISSN: 0741-5214 ISO Abbreviation: J. Vasc. Surg. Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-10-24 Completed Date: 2005-12-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: United States |
Other Details:
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Languages: eng Pagination: 796-9 Citation Subset: IM |
Affiliation:
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Department of Surgery, The George Washington University School of Medicine, Washington, DC, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angiography Arterial Occlusive Diseases / etiology*, pathology, radiography, surgery* Biopsy, Needle Brachial Artery / pathology, radiography, surgery* Female Follow-Up Studies Humans Hypereosinophilic Syndrome / complications*, diagnosis Immunohistochemistry Risk Assessment Treatment Outcome Vascular Patency Vascular Surgical Procedures / methods |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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