Document Detail


Brachial arterial dynamics during staged lower extremity exercise: utility and comparison in physically active versus sedentary subjects.
MedLine Citation:
PMID:  18001359     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Constriction and relaxation of peripheral conduit arteries in response to exercise and recovery are amenable to noninvasive imaging. Diameter changes in the brachial artery during stationary bicycle pedaling are paradoxical to those in the lower extremities. When exercise is confined to the legs, arteries in the upper extremities constrict while leg arteries dilate. The magnitude of vasoconstriction in the upper extremities reflects the integrity of exercise mediated vascular responses. In the current study, young and old men with various levels of physical activity and cardiovascular histories exercised on a stationary bicycle while brachial artery diameter and flow velocity were continuously obtained. Results suggest that normal aging blunts arterial reactivity in seniors even if they exercise regularly. However, arterial dysfunction is greater when associated with sedentary lifestyle. This methodology of imaging brachial artery diameter changes during bicycle pedaling appears to be an effective tool for assessing the physiologic integrity of the vascular bed.
Authors:
Alexander J Muster; Bonnie Kane; Hyunggun Kim; David D McPherson
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  24     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-16     Completed Date:  2008-01-29     Revised Date:  2011-09-26    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1058-64     Citation Subset:  IM    
Affiliation:
Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aging / physiology*
Blood Flow Velocity / physiology
Brachial Artery / physiology*
Exercise / physiology*
Exercise Test
Follow-Up Studies
Humans
Leg / physiology
Male
Motor Activity / physiology*
Rest / physiology*
Sports / physiology
Vasoconstriction / physiology*
Vasodilation / physiology*
Grant Support
ID/Acronym/Agency:
R01 HL074002-07/HL/NHLBI NIH HHS; R56 HL059586-08/HL/NHLBI NIH HHS; UL1 RR024148-03/RR/NCRR NIH HHS
Comments/Corrections

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