| Brachial artery differential characteristic impedance: Contributions from changes in young's modulus and diameter. | |
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MedLine Citation:
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PMID: 19363653 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This examination of brachial artery (BA) differential characteristic impedance, DeltaZ (c), illustrates that changes in Z (c) can occur from changes in either BA wall stiffness (Young's modulus, E) and/or its diameter, D. Furthermore, we assessed how changes in both E and D combine in either an isolated, synergistic, or antagonistic manner to yield the net change in BA Z (c). The basis of this analysis is a partial differential equation which approximates DeltaZ (c) as a total differential. The effects on BA DeltaZ (c) of acetylcholine, atenolol, fenoldapine, nitroglycerin, hydrochlorothiazide and other medications are examined using data from previously published studies. Clinical situations which alter BA Z (c), such as congestive heart failure, hypertension, and hyperemia, are also analyzed. Results illustrate the usefulness of the present approach in differentiating how medications, hyperemia, and pathological conditions affect BA DeltaZ (c) by causing independent changes to E and/or D. |
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Authors:
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Glen Atlas; John K-J Li |
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Publication Detail:
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Type: Journal Article Date: 2009-04-11 |
Journal Detail:
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Title: Cardiovascular engineering (Dordrecht, Netherlands) Volume: 9 ISSN: 1573-6806 ISO Abbreviation: Cardiovasc Eng Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-05-27 Completed Date: 2009-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101132083 Medline TA: Cardiovasc Eng Country: Netherlands |
Other Details:
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Languages: eng Pagination: 11-7 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology, University of Medicine and Dentistry of New Jersey, Newark, 07103, USA. atlasgm@umdnj.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity
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physiology* Blood Pressure / physiology* Brachial Artery / anatomy & histology*, physiology* Computer Simulation Elastic Modulus / physiology Electric Impedance Humans Models, Cardiovascular* Vascular Resistance / physiology |
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