Document Detail

Bowen's disease of the anal and perianal area. A report and analysis of twelve cases.
MedLine Citation:
PMID:  371426     Owner:  NLM     Status:  MEDLINE    
Retrospective evaluation of twelve patients treated at the Cleveland Clinic for perianal Bowen's disease showed that these patients can be cured by wide local excision with skin grafting when necessary. No recurrence or metastasis was found during the follow-up period when the systematic technic was used. Only involved anal mucosa was removed, and normal mucosa was preserved; this aids in controlling anal continence. The margins of the resected skin must be subjected to frozen section study to be sure that total excision has been achieved. In this study a diagnosis of perianal Bowen's disease was made incidentally in six of the twelve patients during histologic examination of anorectal tissue removed for other reasons. Seven of the twelve either had had a systemic or cutaneous cancer previously or another systemic or cutaneous cancer subsequently developed, indicating the high association between Bowen's disease and other cancers. Therefore, it is important that all excised skin from anal or perianal operations be submitted for histologic examination, and if the diagnosis is Bowen's disease, the lesion must be completely removed using wide local excision. These patients should be evaluated and followed up because other malignancies may be present or evolve at a later time.
R J Strauss; V W Fazio
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  137     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1979 Feb 
Date Detail:
Created Date:  1979-05-23     Completed Date:  1979-05-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  231-4     Citation Subset:  AIM; IM    
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MeSH Terms
Anus Neoplasms / pathology,  surgery*
Bowen's Disease / complications,  pathology,  surgery*
Carcinoma in Situ / complications
Carcinoma, Squamous Cell / surgery*
Hemorrhoids / complications
Middle Aged
Skin Neoplasms / pathology,  surgery*
Skin Transplantation
Vulvar Neoplasms / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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