Document Detail

Bowenoid change in perianal condyloma acuminatum associated with ulcerative colitis.
MedLine Citation:
PMID:  1937377     Owner:  NLM     Status:  MEDLINE    
A 35-year-old male patient with a 20-year history of ulcerative colitis developed an itching perianal condyloma acuminatum with discharge. This was surgically removed after two years. Histology revealed bowenoid change in the condyloma. Six months later a local recurrence was excised. He has now been free of further recurrence for 5 years. Electron microscopy showed moderately differentiated keratinocytes in the areas of bowenoid change. There was no evidence of virus particles in the keratinocytes. A causal relationship has been assumed between the ulcerative colitis, via chronic irritation, and the perianal bowenoid changes regarded as in situ carcinoma. The importance of radical excision of such lesions is emphasized.
M Balázs
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  38     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-11-27     Completed Date:  1991-11-27     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  311-3     Citation Subset:  IM    
Department of Pathology, János Hospital, Budapest, Hungary.
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MeSH Terms
Anal Canal / pathology*
Anus Neoplasms / complications,  pathology*,  surgery
Bowen's Disease / pathology
Carcinoma in Situ / pathology
Colitis, Ulcerative / complications*
Condylomata Acuminata / complications,  pathology*,  surgery
Microscopy, Electron
Skin Neoplasms / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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