Document Detail


Bowel preparation prior to colonoscopy: a continual search for excellence.
MedLine Citation:
PMID:  23345936     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bowel preparation prior to colonoscopy is essential to maximize the benefits of colonoscopy. Numerous bowel preparations have been studied, ranging from 4 L polyethylene glycol (PEG) to split-dose regimens to 2 L PEG with an adjunct laxative (senna, bisacodyl, ascorbic acid). Due to the large volume of PEG required for adequate bowel preparation, many studies have focused on reducing this large volume to only 2 L PEG with the addition of an adjunct. Recently, a randomized controlled trial by Tajika et al showed that the addition of mosapride to only 1.5 L PEG was non-inferior to mosapride and 2 L PEG for bowel cleansing but did provide improvements in patient tolerance. This study offers yet another potential bowel preparation for patients undergoing colonoscopy and may trigger further studies with 1.5 L PEG with an adjunct. In this letter, we discuss the current state of bowel preparation prior to colonoscopy and offer information to guide clinicians on choosing the appropriate bowel preparation for their patients.
Authors:
Matthew L Bechtold; Abhishek Choudhary
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  19     ISSN:  2219-2840     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-24     Completed Date:  2014-02-14     Revised Date:  2014-05-20    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  155-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Benzamides / therapeutic use
Cathartics / therapeutic use*
Colonoscopy / methods*
Humans
Morpholines / therapeutic use
Polyethylene Glycols / therapeutic use
Treatment Outcome
Chemical
Reg. No./Substance:
0/Benzamides; 0/Cathartics; 0/Morpholines; 0/Polyethylene Glycols; I8MFJ1C0BY/mosapride
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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