Document Detail

Bowel function of long-term tube-fed patients consuming formulae with and without dietary fiber.
MedLine Citation:
PMID:  2172578     Owner:  NLM     Status:  MEDLINE    
Diarrhea, constipation and subsequent laxative use are chronic problems in long-term enterally fed patients. We have conducted a double-blind randomized crossover study to evaluate the effects of two enteral formulae (Enrich, 12.8 g of dietary fiber per 1000 kcal and Ensure, fiber-free) on stool frequency, fecal weight, laxative use, gastrointestinal tolerance and bowel function in chronic care tube-fed patients. Twenty-eight subjects (24 male, 4 female) completed the study. Mean daily number of stools and mean daily fecal wet weight in Enrich-fed patients were not significantly different from those of patients receiving Ensure. Ensure-fed patients required significantly more laxatives (p = 0.02) than those receiving Enrich. There were 26 reports of diarrhea in the Ensure-fed group as compared to 6 in the Enrich-fed group, and this difference was significant (p = 0.006). Reporting rates for constipation were not significantly different in the two groups. At the end of the study, the bowel function of 57.1% of patients receiving Enrich was improved when compared with that of 14.3% of Ensure-fed patients, and this difference was significant (p = 0.005). These results suggest that the addition of dietary fiber to enteral formulae improves gastrointestinal tolerance and bowel function, and reduces laxative use in long-term enterally fed patients.
K Shankardass; S Chuchmach; K Chelswick; C Stefanovich; S Spurr; J Brooks; M Tsai; F G Saibil; L B Cohen; J D Edington
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  14     ISSN:  0148-6071     ISO Abbreviation:  JPEN J Parenter Enteral Nutr     Publication Date:    1990 Sep-Oct
Date Detail:
Created Date:  1990-12-19     Completed Date:  1990-12-19     Revised Date:  2007-02-21    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  508-12     Citation Subset:  IM    
Chedoke-McMaster Hospitals, Hamilton, Ontario, Canada.
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MeSH Terms
Aged, 80 and over
Defecation / drug effects*
Dietary Fiber / administration & dosage,  pharmacology*
Enteral Nutrition / methods*
Food, Formulated
Intestine, Large / drug effects*
Middle Aged
Time Factors
Comment In:
JPEN J Parenter Enteral Nutr. 1992 May-Jun;16(3):297   [PMID:  1323722 ]
JPEN J Parenter Enteral Nutr. 1992 Jan-Feb;16(1):91-2   [PMID:  1310787 ]

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