Document Detail

Bovine pericardial patch repair in infected fields.
MedLine Citation:
PMID:  22459752     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Bovine pericardial patches (BPP) are frequently used for arterial reconstruction, but little data exist regarding their ability to resist infection. We hypothesize that BPP would provide a reasonable alternative to autologous vein patches in infected fields.
METHODS: We used BPP to repair 51 arteriotomies (25 brachial, 23 femoral, three popliteal) in 48 consecutive patients (mean age, 68 years; 65% men, 75% diabetic, 67% dialysis dependent) undergoing removal of infected (33 gram-positive, three gram-negative, eight mixed flora, and four culture-negative) polytetrafluoroethylene grafts (35 arteriovenous grafts, nine femoral-distal bypasses, and four femoral patch angioplasties) between January 2007 and January 2011. Patient records were retrospectively reviewed and outcomes, including death, rupture, secondary reconstruction, and infection, were recorded.
RESULTS: Over a mean follow-up of 2.1 years (range, 3-48 months), 50 of 51 patches remained in place without evidence of recurrent infection, rupture, or revision. One patient had acute rupture of a popliteal arteriotomy 1 week postrepair and had subsequent ligation and above-knee amputation. Eight of the 48 patients died from unrelated causes during follow-up (three withdrew from dialysis, three myocardial infarction, and two unknown).
CONCLUSIONS: BPP provide a durable alternative to saphenous vein for arterial reconstruction following removal of infected arterial grafts.
William D McMillan; Christopher D Leville; Chantel N Hile
Publication Detail:
Type:  Journal Article     Date:  2012-03-28
Journal Detail:
Title:  Journal of vascular surgery     Volume:  55     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-21     Completed Date:  2012-07-18     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1712-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
Minneapolis Vascular Physicians, Plymouth, MN 55456, USA.
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MeSH Terms
Aged, 80 and over
Anti-Bacterial Agents / therapeutic use
Blood Vessel Prosthesis / adverse effects*
Blood Vessel Prosthesis Implantation / adverse effects*,  instrumentation,  mortality
Combined Modality Therapy
Device Removal
Limb Salvage
Middle Aged
Pericardium / transplantation*
Prosthesis-Related Infections / drug therapy,  microbiology,  mortality,  surgery*
Retrospective Studies
Surgical Flaps
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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