| Botulism. | |
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MedLine Citation:
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PMID: 16163636 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Botulism is a rare disease with 4 naturally occurring syndromes: foodborne botulism is caused by ingestion of foods contaminated with botulinum toxin, wound botulism is caused by Clostridium botulinum colonization of a wound and in situ toxin production, infant botulism is caused by intestinal colonization and toxin production, and adult intestinal toxemia botulism is an even rarer form of intestinal colonization and toxin production in adults. Inhalational botulism could result from aerosolization of botulinum toxin, and iatrogenic botulism can result from injection of toxin. All forms of botulism produce the same distinct clinical syndrome of symmetrical cranial nerve palsies followed by descending, symmetric flaccid paralysis of voluntary muscles, which may progress to respiratory compromise and death. The mainstays of therapy are meticulous intensive care (including mechanical ventilation, when necessary) and timely treatment with antitoxin. |
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Authors:
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Jeremy Sobel |
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Publication Detail:
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Type: Journal Article; Review Date: 2005-08-29 |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 41 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-09-15 Completed Date: 2006-09-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 1167-73 Citation Subset: IM |
Affiliation:
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Foodborne and Diarrheal Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. jsobel@cdc.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Botulinum Antitoxin
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therapeutic use Botulism / diagnosis*, therapy* Clostridium botulinum / metabolism Food Microbiology Humans Intensive Care |
| Chemical | |
Reg. No./Substance:
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0/Botulinum Antitoxin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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