| Botulinum toxin type A in the healing of a chronic buttock ulcer in a patient with spastic paraplegia after spinal cord injury. | |
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MedLine Citation:
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PMID: 19894009 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Pressure sores are a significant secondary complication in spinal cord injured patients. A new indication for botulinum toxin type A is described here, in treatment of recurrent muscular spasms that had hampered the healing of a chronic buttock ulcer in a subject with severe spastic paraplegia. CASE REPORT: A 27-year-old man with spastic paraplegia following traumatic spinal cord lesion at the thoracic level had developed recurrent severe muscular spasms, particularly involving the buttock region, with an Ashworth scale score of 3-4 and a Spasm Frequency Scale of grade 4. The patient had a pressure ulcer in the left gluteal region (grade IV according to the European Pressure Ulcer Advisory Panel (EPUAP). Several treatments were administered without success, and all efforts at healing the ulcer by topical medication were hampered by recurrent spasms involving the buttock muscles and ulcer region. The left gluteus maximus muscle was treated with 2 infiltrations of 660 IU botulinum toxin type A. The use of botulinum toxin type A allowed better care of the pressure ulcer, which had healed by 6 months after the initial infiltration. CONCLUSION: The use of botulinum toxin type A may be an important adjunctive therapy for treatment of pathological conditions involving recalcitrant involuntary muscle contraction. |
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Authors:
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Domenico Intiso; Mario Basciani |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation Medicine Volume: 41 ISSN: 1651-2081 ISO Abbreviation: J Rehabil Med Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-11-06 Completed Date: 2009-11-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101088169 Medline TA: J Rehabil Med Country: Sweden |
Other Details:
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Languages: eng Pagination: 1100-2 Citation Subset: IM |
Affiliation:
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Department of Neuro-Rehabilitation, Scientific Institute Hospital Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy. d.intiso@operapadrepio.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Botulinum Toxin Type A / therapeutic use* Buttocks* Chronic Disease Humans Male Muscle Spasticity / complications, drug therapy*, etiology Neuromuscular Agents / therapeutic use* Paraplegia / complications* Pressure Ulcer / drug therapy* Recurrence Spinal Cord Injuries / complications* Wound Healing / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Botulinum Toxin Type A; 0/Neuromuscular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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