Document Detail

Botulinum toxin type A gives adjunctive benefit to periorbital laser resurfacing.
MedLine Citation:
PMID:  15545098     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Periorbital aging and lines are a result of intrinsic skin aging, ultraviolet damage, and repetitive action of periorbital muscles. Rejuvenation of this area should therefore be optimized by combining treatments that approach the different causative factors. METHODS: This was a single-center, prospective, randomized, placebo-controlled study comparing the efficacy and safety of combining Botox injections (18 units per area) with ablative laser resurfacing versus laser resurfacing alone without Botox in the treatment of periorbital rhytids. RESULTS: We have concluded a bilateral study comparing the effects of Botox versus saline placebo injections to the periorbital areas before and following erbium: YAG laser resurfacing of the areas in 33 patients. The results demonstrated that the Botox-treated side with laser resurfacing improved significantly more than the contralateral area treated with saline and laser in diminishing periorbital rhytids as well as textural, pigmentation, and other features of periorbital skin aging. CONCLUSION: This study illustrates the benefits of a combined approach to treating periorbital skin aging.
Paul S Yamauchi; GaryP Lask; Nicholas J Lowe
Related Documents :
19593638 - Effects of diode laser therapy on the acellular dermal matrix.
18318728 - Treatment of facial telangiectasia using a dual-wavelength laser system (595 and 1,064 ...
20331348 - Adverse effects following q-switched ruby laser treatment of pigmented lesions.
25304478 - The effect of gowning on labor epidural catheter colonization rate: a randomized contro...
19090828 - Effect of different combinations of cryoprotectants on in vitro maturation of immature ...
8507018 - Comparison of nalbuphine and fentanyl as intravenous analgesics for medically compromis...
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology     Volume:  6     ISSN:  1476-4172     ISO Abbreviation:  J Cosmet Laser Ther     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-11-16     Completed Date:  2005-04-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101136419     Medline TA:  J Cosmet Laser Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  145-8     Citation Subset:  IM    
UCLA School of Medicine, Los Angeles, CA, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Botulinum Toxin Type A / administration & dosage*
Cosmetic Techniques*
Facial Muscles / physiology
Laser Therapy*
Muscle Contraction
Skin Aging*
Reg. No./Substance:
0/Botulinum Toxin Type A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Clinical evaluation of non-ablative radiofrequency facial rejuvenation.
Next Document:  Resolution of retracted scar after 585-nm pulse dye laser surgery.