Document Detail

Botulinum toxin for benign essential blepharospasm, hemifacial spasm and age-related lower eyelid entropion.
MedLine Citation:
PMID:  3815164     Owner:  NLM     Status:  MEDLINE    
Purified botulinum A exotoxin was used in the treatment of forty seven patients with benign essential blepharospasm, 11 patients with hemifacial spasm and 2 patients with age-related entropion. The treatment was effective in all three groups for an average of 3-4 months when symptoms recurred and repeated chemodenervation with toxin was needed. The commonest complication was transient ptosis with an overall frequency of 7.8%. This incidence increased to 11.1% with toxin doses higher than 25 units per orbicularis. The treatment was well accepted by the patients, who were subsequently able to return to pre-blepharospasm lifestyles.
J Carruthers; H A Stubbs
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques     Volume:  14     ISSN:  0317-1671     ISO Abbreviation:  Can J Neurol Sci     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-04-23     Completed Date:  1987-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0415227     Medline TA:  Can J Neurol Sci     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  42-5     Citation Subset:  IM    
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MeSH Terms
Blepharospasm / drug therapy*
Botulinum Toxins / administration & dosage,  adverse effects,  therapeutic use*
Entropion / drug therapy*
Eyelid Diseases / drug therapy*
Facial Muscles*
Middle Aged
Spasm / drug therapy*
Reg. No./Substance:
0/Botulinum Toxins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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