Document Detail


Botulinum neurotoxin-A treatment of lower urinary tract symptoms in multiple sclerosis.
MedLine Citation:
PMID:  24454606     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Multiple sclerosis (MS) is the most common neuroinflammatory disease of the central nervous system and a leading cause of disability in young adults. Symptoms related to vesicourethral dysfunction are very prevalent, but not specific to underlying urodynamic abnormalities. Detrusor overactivity and detrusor external sphincter dysynergia are the most frequent findings and are usually linked. Botulinum neurotoxin-A injection represents a significant advance in the management of voiding dysfunction among MS patients failing first-line therapy. It significantly improves patients' urodynamic parameters and quality of life, with efficacy sustained by repeated injections and minimal risk of adverse events.
Authors:
Oussama El Yazami Adli; Jacques Corcos
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Canadian Urological Association journal = Journal de l'Association des urologues du Canada     Volume:  8     ISSN:  1911-6470     ISO Abbreviation:  Can Urol Assoc J     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-01-23     Completed Date:  2014-06-24     Revised Date:  2014-06-24    
Medline Journal Info:
Nlm Unique ID:  101312644     Medline TA:  Can Urol Assoc J     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  E61-7     Citation Subset:  -    
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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