| Botryomycosis in acquired immunodeficiency syndrome. | |
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MedLine Citation:
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PMID: 3827528 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The first case, to our knowledge, of an integumentary form of botryomycosis is reported in a homosexual man with acquired immunodeficiency syndrome. Anal fistula and ischiorectal and gluteal abscesses developed following severe cryptosporidial diarrhea. Grains composed of gram-positive cocci were identified in the suppurative exudate. The grains had attached to multinucleated macrophages, many of which contained clusters of cocci in their cytoplasm. It is postulated that the cocci were able to survive and probably replicate in the cytoplasm of multinucleated macrophages, and were subsequently extruded as grains. These observations suggest a defect in intracellular killing of cocci by the monocyte-macrophage system. This may relate to failure in induction of control of macrophage activity by T4-inducer subsets. |
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Authors:
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I R Toth; H L Kazal |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of pathology & laboratory medicine Volume: 111 ISSN: 0003-9985 ISO Abbreviation: Arch. Pathol. Lab. Med. Publication Date: 1987 Mar |
Date Detail:
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Created Date: 1987-03-30 Completed Date: 1987-03-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7607091 Medline TA: Arch Pathol Lab Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 246-9 Citation Subset: AIM; IM; X |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abscess
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etiology Acquired Immunodeficiency Syndrome / complications* Adult Bacterial Infections / etiology*, pathology Connective Tissue / pathology Granuloma / etiology*, pathology Humans Male Rectal Diseases / etiology*, pathology Rectal Fistula / etiology |
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