| Botryllamides E-H, four new tyrosine derivatives from the ascidian Botrylloides tyreum. | |
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MedLine Citation:
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PMID: 15217298 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A specimen of the ascidian Botrylloides tyreum from Palau contained the known metabolites botryllamides A (5) and C (7) together with four new tyrosine derivatives, botryllamides E-H (1-4), the structures of which were elucidated by interpretation of spectroscopic data. The botryllamides exhibited weak cytotoxicity against the HCT-116 cell line. |
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Authors:
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M Rama Rao; D John Faulkner |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of natural products Volume: 67 ISSN: 0163-3864 ISO Abbreviation: J. Nat. Prod. Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-06-25 Completed Date: 2004-08-09 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7906882 Medline TA: J Nat Prod Country: United States |
Other Details:
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Languages: eng Pagination: 1064-6 Citation Subset: IM |
Affiliation:
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Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093-0212, USA. rmanam@nereuspharm.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antineoplastic Agents / chemistry, isolation & purification*, pharmacology Drug Screening Assays, Antitumor Humans Molecular Structure Nuclear Magnetic Resonance, Biomolecular Palau Tumor Cells, Cultured Tyrosine / analogs & derivatives*, chemistry, isolation & purification*, pharmacology Urochordata / chemistry* |
| Grant Support | |
ID/Acronym/Agency:
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CA 49084/CA/NCI NIH HHS; CA 67775/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 55520-40-6/Tyrosine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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