Document Detail

Both high and low blood pressures risk indicators of death in middle-aged males. Isotonic regression of blood pressure on age applied to data from a 13-year prospective study.
MedLine Citation:
PMID:  4091047     Owner:  NLM     Status:  MEDLINE    
This study was performed to investigate whether a moderately sized population of men (n = 954) living in a geographically defined area could be utilized and give valid results in a 13-year prospective study regarding mortality as a function of blood pressure. Isotonic regression of blood pressure on age was used to define groups of men with low, medium, and high blood pressure. Men aged 40-69 years in both extreme groups showed an excess death risk in comparison with those in the medium group. Thus, mortality appeared to be a U-shaped function of blood pressure in this age group. The mortality ratios of the low and high blood pressure groups vis-à-vis the medium group were higher during the first than during the second half of the observation period. Chronic diseases at the time of the initial examination were more common among men who died in the lowest blood pressure group than among those who died in the medium group. In males aged 70-99 years, blood pressure appeared to be of less importance as a risk indicator of death.
L Lindholm; J Lanke; B Bengtsson; G Ejlertsson; T Thulin; B Scherstén
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta medica Scandinavica     Volume:  218     ISSN:  0001-6101     ISO Abbreviation:  Acta Med Scand     Publication Date:  1985  
Date Detail:
Created Date:  1986-02-26     Completed Date:  1986-02-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370330     Medline TA:  Acta Med Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  473-80     Citation Subset:  IM    
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MeSH Terms
Age Factors
Blood Pressure Determination
Hypertension / mortality*
Hypotension / mortality*
Middle Aged
Prospective Studies
Regression Analysis
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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