Document Detail


Botanicals and anti-inflammatories: natural ingredients for rosacea.
MedLine Citation:
PMID:  21925368     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Rosacea is a chronic inflammatory skin condition characterized by cutaneous hypersensitivity. There are many therapeutic options available for the treatment of rosacea, but none are curative. Since the pathogenesis of rosacea remains elusive, it is not surprising that no single treatment is paramount and that many patients find therapies unsatisfactory or even exacerbating. Treatments are prescribed to work in concert with each other in order to ameliorate the common clinical manifestations, which include: papules and pustules, telangiectasias, erythema, gland hypertrophy, and ocular disease. The most validated topical therapies include metronidazole, azelaic acid, and sodium sulfacetamide-sulfur. Many other topical therapies, such as calcineurin inhibitors, benzoyl peroxide, clindamycin, retinoids, topical corticosteroids, and permethrin have demonstrated varying degrees of success. Due to the inconsistent results of the aforementioned therapies patients are increasingly turning to alternative products containing natural ingredients or botanicals to ease inflammation and remit disease. Additional research is needed to elucidate the benefits of these ingredients in the management of rosacea, but some important considerations regarding the natural ingredients with clinical data will be discussed here.
Authors:
Jason Emer; Heidi Waldorf; Diane Berson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in cutaneous medicine and surgery     Volume:  30     ISSN:  1558-0768     ISO Abbreviation:  Semin Cutan Med Surg     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9617260     Medline TA:  Semin Cutan Med Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  148-55     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Mount Sinai School of Medicine, Department of Dermatology, New York, NY.
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