Document Detail

Boston Ocular Surface Prosthesis for persistent epitheliopathy after treatment of conjunctival melanoma.
MedLine Citation:
PMID:  20164756     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To report two cases of persistent epitheliopathy after treatment of conjunctival melanoma and review management options for this condition.
METHODS: Case report and literature review.
RESULTS: Persistent epitheliopathy, presumably resulting from limbal stem cell deficiency, is an uncommon complication of treatment of conjunctival malignant melanoma with surgical excision, cryotherapy, and mitomycin C. The Boston Ocular Surface Prosthesis was successful in improving vision, comfort, and epithelial status in our patients.
CONCLUSION: Persistent epitheliopathy is a rare complication of treatment of conjunctival melanoma. The Boston Ocular Surface Prosthesis is a viable treatment option in this situation.
Surbhi Grover; Deborah S Jacobs; Kathryn A Colby
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cornea     Volume:  29     ISSN:  1536-4798     ISO Abbreviation:  Cornea     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2011-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  United States    
Other Details:
Languages:  eng     Pagination:  459-61     Citation Subset:  IM    
Harvard Medical School, Boston, MA, USA.
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MeSH Terms
Alkylating Agents / administration & dosage
Artificial Organs
Conjunctival Neoplasms / pathology,  surgery*
Corneal Diseases / etiology,  surgery*
Epithelium, Corneal / pathology,  surgery*
Melanoma / pathology,  surgery*
Middle Aged
Mitomycin / administration & dosage
Postoperative Complications*
Prostheses and Implants*
Prosthesis Implantation*
Reg. No./Substance:
0/Alkylating Agents; 50-07-7/Mitomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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