| Bosentan. | |
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MedLine Citation:
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PMID: 21729856 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BOSENTAN (TRACLEER, Actelion Pharmaceuticals, South San Francisco, CA) is an oral dual endothelin-1 receptor antagonist with proven efficacy and safety in adults with primary pulmonary hypertension (PH).1,2 Several case reports of neonates and former premature infants with PH of varying etiologies demonstrate the potential effectiveness of bosentan in this population. This column will first discuss the role of the endothelin system in PH, describe the mechanism of action of bosentan, and, finally, review the neonatal cases of bosentan use reported in the literature. |
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Authors:
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Susan Givens Bell |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neonatal network : NN Volume: 30 ISSN: 1539-2880 ISO Abbreviation: Neonatal Netw Publication Date: 2011 Jul-Aug |
Date Detail:
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Created Date: 2011-07-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8503921 Medline TA: Neonatal Netw Country: United States |
Other Details:
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Languages: eng Pagination: 249-51 Citation Subset: N |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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