Document Detail

Boron neutron capture therapy for glioblastoma: is it worth pursuing?
MedLine Citation:
PMID:  18198928     Owner:  NLM     Status:  MEDLINE    
Presently glioblastomas are incurable brain tumors. The prospect of treating this deadly disease has been the major justification for the current programs of boron neutron capture therapy (BNCT) throughout the world. However, based on pharmacological and cell biological considerations, it is improbable that BNCT will ever be an effective therapy for this tumor. Indeed, a review of the published literature over the last 50 years fails to provide justification for developing BNCT past its present experimental stage.
Ute Linz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Technology in cancer research & treatment     Volume:  7     ISSN:  1533-0346     ISO Abbreviation:  Technol. Cancer Res. Treat.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-17     Completed Date:  2008-04-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140941     Medline TA:  Technol Cancer Res Treat     Country:  United States    
Other Details:
Languages:  eng     Pagination:  83-8     Citation Subset:  IM    
Forschungszentrum Julich GmbH, D-52425 Julich, Germany.
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MeSH Terms
Boron Neutron Capture Therapy / methods*
Brain Neoplasms / radiotherapy*
Glioblastoma / radiotherapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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