Document Detail


Boron neutron capture therapy (BNCT) in Finland: Technological and physical prospects after 20 years of experiences.
MedLine Citation:
PMID:  22613369     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Boron Neutron Capture Therapy (BNCT) is a binary radiotherapy method developed to treat patients with certain malignant tumours. To date, over 300 treatments have been carried out at the Finnish BNCT facility in various on-going and past clinical trials. In this technical review, we discuss our research work in the field of medical physics to form the groundwork for the Finnish BNCT patient treatments, as well as the possibilities to further develop and optimize the method in the future. Accordingly, the following aspects are described: neutron sources, beam dosimetry, treatment planning, boron imaging and determination, and finally the possibilities to detect the efficacy and effects of BNCT on patients.
Authors:
Sauli Savolainen; Mika Kortesniemi; Marjut Timonen; Vappu Reijonen; Linda Kuusela; Jouni Uusi-Simola; Eero Salli; Hanna Koivunoro; Tiina Seppälä; Nadja Lönnroth; Petteri Välimäki; Heini Hyvönen; Petri Kotiluoto; Tom Serén; Antti Kuronen; Sami Heikkinen; Antti Kosunen; Iiro Auterinen
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-19
Journal Detail:
Title:  Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)     Volume:  -     ISSN:  1724-191X     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9302888     Medline TA:  Phys Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Department of Physics, University of Helsinki, Finland; HUS Helsinki Medical Imaging Center, Helsinki University Central Hospital, Finland.
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