Document Detail


Borderline papillary serous tumor of the fimbriated end of the fallopian tube with peritoneal implants.
MedLine Citation:
PMID:  21651651     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Diagnosis of Borderline papillary serous tumor of the fallopian tube was comprehensively established by Zheng in 1996 supported mostly by a histological similarity to its ovarian counterpart. It is a very rare entity with eight cases published so far and the ninth case described here as a 41-year-old woman presented with non-specific lower abdominal pain, dyspareunia and dysuria. Left adnexal mass was identified and she was operated on. It turned out the tumor was attached exclusively to the left tube, with no connection to any of the surrounding structures and with histology of borderline serous tumor with non-invasive implants in the left and right ovary and visceral peritoneum. Reviewing available data on genetics of these tumors there was diploid status in one examined tumor, and in our case no mutations of KRAS, BRAF and p53 genes were found. Histomorphology remains the mainstay of diagnosis and staging operation is the mainstay of patient management. Prognosis is uncertain with a 6-year survival documented in one case.
Authors:
Ondrej Ondic; Vladimir Kalis; Radek Sima
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-06-09
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  37     ISSN:  1447-0756     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-10-28     Completed Date:  2012-02-23     Revised Date:  2012-06-21    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  1702-5     Citation Subset:  IM    
Copyright Information:
© 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology.
Affiliation:
Sikl's Department of Pathology, University Hospital, Faculty of Medicine, Charles University, Czech Republic. ondic@medima.cz
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MeSH Terms
Descriptor/Qualifier:
Adult
Cystadenocarcinoma, Serous / genetics,  pathology*,  surgery
Fallopian Tube Neoplasms / genetics,  pathology*,  surgery
Fallopian Tubes / pathology*,  surgery
Female
Humans
Peritoneal Neoplasms / genetics,  pathology*,  surgery
Proto-Oncogene Proteins B-raf / genetics
Chemical
Reg. No./Substance:
EC 2.7.11.1/BRAF protein, human; EC 2.7.11.1/Proto-Oncogene Proteins B-raf

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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