| Border-cell migration: the race is on. | |
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MedLine Citation:
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PMID: 12511865 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion. |
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Authors:
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Denise J Montell |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Nature reviews. Molecular cell biology Volume: 4 ISSN: 1471-0072 ISO Abbreviation: Nat. Rev. Mol. Cell Biol. Publication Date: 2003 Jan |
Date Detail:
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Created Date: 2003-01-03 Completed Date: 2003-02-10 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 100962782 Medline TA: Nat Rev Mol Cell Biol Country: England |
Other Details:
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Languages: eng Pagination: 13-24 Citation Subset: IM |
Affiliation:
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Department of Biological Chemistry, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205-2185, USA. dmontell@jhmi.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Movement / physiology* Drosophila melanogaster / cytology, embryology* Epithelial Cells / cytology* Female Gene Expression Regulation, Developmental Ovary / cytology* Signal Transduction / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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