Document Detail


Bone scintigraphy as a prognostic factor in patients with adult T-cell leukemia-lymphoma.
MedLine Citation:
PMID:  7842597     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bone scintigraphy in 26 patients with adult T-cell leukemia-lymphoma (ATLL) was evaluated. Abnormally high accumulations were observed in 7 of 26 patients (skull, 5; vertebra, 1; rib, 6; bony pelvis, 1; scapula, 2; lower extremities, 1). Serum calcium levels were significantly elevated in patients with abnormally high accumulations on bone scintigraphy. Survival rates of the patients with positive results on bone scintigraphy were significantly lower than were those with negative results on bone scintigraphy (P < 0.05). Survival rates of patients with high serum calcium levels, high WBC counts, and high serum lactate dehydrogenase (LDH) levels were also significantly lower than were those of the negative groups, in this order of significance. Bone scintigraphy was useful for detecting bone marrow involvement in ATLL and it can be one of the better indicators of the prognoses of patients with ATLL.
Authors:
H Hoshi; S Nagamachi; S Jinnouchi; T Ohnishi; F Shigemi; K Watanabe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  19     ISSN:  0363-9762     ISO Abbreviation:  Clin Nucl Med     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-03-07     Completed Date:  1995-03-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  992-5     Citation Subset:  IM; X    
Affiliation:
Department of Radiology, Miyazaki Medical College, Japan.
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MeSH Terms
Descriptor/Qualifier:
Bone and Bones / radionuclide imaging*
Calcium / blood
Female
Humans
L-Lactate Dehydrogenase / blood
Leukemia-Lymphoma, Adult T-Cell / blood,  mortality*,  radionuclide imaging*
Leukocyte Count
Male
Middle Aged
Prognosis
Survival Rate
Technetium Tc 99m Medronate / diagnostic use*
Chemical
Reg. No./Substance:
63347-66-0/Technetium Tc 99m Medronate; 7440-70-2/Calcium; EC 1.1.1.27/L-Lactate Dehydrogenase

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