Document Detail


Bone loss and muscle atrophy in spinal cord injury: epidemiology, fracture prediction, and rehabilitation strategies.
MedLine Citation:
PMID:  17274487     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Individuals with spinal cord injury (SCI) often experience bone loss and muscle atrophy. Muscle atrophy can result in reduced metabolic rate and increase the risk of metabolic disorders. Sublesional osteoporosis predisposes individuals with SCI to an increased risk of low-trauma fracture. Fractures in people with SCI have been reported during transfers from bed to chair, and while being turned in bed. The bone loss and muscle atrophy that occur after SCI are substantial and may be influenced by factors such as completeness of injury or time postinjury. A number of interventions, including standing, electrically stimulated cycling or resistance training, and walking exercises have been explored with the aim of reducing bone loss and/or increasing bone mass and muscle mass in individuals with SCI. Exercise with electrical stimulation appears to increase muscle mass and/or prevent atrophy, but studies investigating its effect on bone are conflicting. Several methodological limitations in exercise studies with individuals with SCI to date limit our ability to confirm the utility of exercise for improving skeletal status. The impact of standing or walking exercises on muscle and bone has not been well established. Future research should carefully consider the study design, skeletal measurement sites, and the measurement techniques used in order to facilitate sound conclusions.
Authors:
Lora Giangregorio; Neil McCartney
Related Documents :
6717067 - Increased in vitro radioresistance of bone marrow fibroblastic progenitors (cfu-f) from...
14522647 - Seat influences on female neck responses in rear crashes: a reason why women have highe...
10670687 - Production and physical characteristics of composted poultry carcases.
8375357 - The effects of a 5-month physical training on iliac bone morphology in monkeys.
22247297 - Assessment and prevention of exercise-induced bronchoconstriction.
9113537 - Patellofemoral design influences function following total knee arthroplasty.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The journal of spinal cord medicine     Volume:  29     ISSN:  1079-0268     ISO Abbreviation:  J Spinal Cord Med     Publication Date:  2006  
Date Detail:
Created Date:  2007-02-05     Completed Date:  2007-02-15     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  9504452     Medline TA:  J Spinal Cord Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  489-500     Citation Subset:  IM    
Affiliation:
Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada. lmgiangr@uwaterloo.ca
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Electric Stimulation Therapy
Exercise / physiology
Fractures, Bone / etiology*,  prevention & control
Humans
Muscular Atrophy / etiology*,  prevention & control,  rehabilitation
Osteoporosis / etiology*,  prevention & control,  rehabilitation
Predictive Value of Tests
Prevalence
Risk Factors
Spinal Cord Injuries / complications*,  physiopathology,  rehabilitation
Walking / physiology
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  G. Heiner Sell memorial lecture: neuronal plasticity after spinal cord injury: significance for pres...
Next Document:  Incidence, etiology, and risk factors for fever following acute spinal cord injury.