| Bone health in patients with fibromyalgia. | |
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MedLine Citation:
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PMID: 12810939 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To determine whether women with fibromyalgia are at increased risk of developing osteoporosis or osteomalacia. METHODS: Forty premenopausal women with fibromyalgia and 37 age-matched female controls were studied. Broadband ultrasound attenuation (BUA) and velocity of sound (VOS) were measured at the calcaneum and bone mineral density was measured at the forearm and lumbar spine using dual-energy X-ray absorptiometry. Serum calcium, alkaline phosphatase, gamma-glutamyl transferase, 25-hydroxyvitamin D and plasma viscosity were measured in all subjects and parathyroid hormone was measured in subjects recruited in the latter part of the study. RESULTS: Seventeen patients with fibromyalgia syndrome and seven controls had 25-hydroxyvitamin D concentrations <20 nmol/l (P < 0.015) and in three FMS patients serum parathyroid hormone was raised. Bone density in fibromyalgia patients was slightly lower at the mid-distal forearm but comparable to that in controls at other sites. CONCLUSIONS: There is no reason to recommend routine bone densitometry in fibromyalgia patients. However, vitamin D subnutrition is common in these patients and this should be sought. |
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Authors:
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A W Al-Allaf; P A Mole; C R Paterson; T Pullar |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2003-06-16 |
Journal Detail:
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Title: Rheumatology (Oxford, England) Volume: 42 ISSN: 1462-0324 ISO Abbreviation: Rheumatology (Oxford) Publication Date: 2003 Oct |
Date Detail:
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Created Date: 2003-09-25 Completed Date: 2003-11-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100883501 Medline TA: Rheumatology (Oxford) Country: England |
Other Details:
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Languages: eng Pagination: 1202-6 Citation Subset: AIM; IM |
Affiliation:
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University Department of Medicine, Ninewells Hospital and Medical School, Dundee, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorptiometry, Photon Adult Bone Density Case-Control Studies Female Fibromyalgia / blood, complications*, physiopathology Humans Middle Aged Osteomalacia / etiology Osteoporosis / etiology* Premenopause / blood, physiology Vitamin D / analogs & derivatives*, blood |
| Chemical | |
Reg. No./Substance:
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1406-16-2/Vitamin D; 64719-49-9/25-hydroxyvitamin D |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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