Document Detail

Bone composition measured by x-ray scattering.
MedLine Citation:
PMID:  1626026     Owner:  NLM     Status:  MEDLINE    
Ten composite samples consisting of cortical bone and adipose tissue, in known proportions, were made. The intensity of monochromatic x-rays (energy 8 keV) scattered by these samples was determined as a function of the modulus of the scattering vector, K. The ratio of the heights of peaks at K values of around 134 and 22 nm-1 provided a measure of the ratio of adipose tissue to bone mineral in these samples. This method was then used to determine the ratio of adipose tissue to mineral in samples of trabecular bone from 16 vertebral bodies. The results were correlated with measurements of the bone composition determined by ashing (r = 0.66) and histomorphometry (r = 0.66). Furthermore, the ashing and histomorphometry results were correlated with each other (r = 0.68). The feasibility of using higher energy x-rays (35-80 keV) for obtaining the same information from bone within the body is briefly discussed.
M Newton; D W Hukins; G Harding
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Physics in medicine and biology     Volume:  37     ISSN:  0031-9155     ISO Abbreviation:  Phys Med Biol     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-08-13     Completed Date:  1992-08-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1339-47     Citation Subset:  IM    
Department of Medical Biophysics, University of Manchester, UK.
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MeSH Terms
Adipose Tissue / chemistry*
Bone Density*
Bone and Bones / chemistry*
Scattering, Radiation*

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