| Bone and wound healing in the diabetic patient. | |
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MedLine Citation:
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PMID: 20682414 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Impaired soft tissue regeneration and delayed osseous healing are known complications associated with diabetes mellitus with regard to orthopedic surgery, making the management and treatment of diabetic patients undergoing foot and ankle surgery more complex and difficult. At the moment several options are available to address the known issues that complicate the clinical outcomes in these high-risk patients. Using a multifaceted approach, with close attention to intraoperative and perioperative considerations including modification of surgical technique to supplement fixation, local application of orthobiologics, tight glycemic control, administration of supplementary oxygen, and biophysical stimulation via low-intensity pulsed ultrasound and electrical bone stimulation, the impediments associated with diabetic healing can potentially be overcome, to yield improved clinical results for diabetic patients after acute or elective foot and ankle surgery. |
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Authors:
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Siddhant K Mehta; Eric A Breitbart; Wayne S Berberian; Frank A Liporace; Sheldon S Lin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Foot and ankle clinics Volume: 15 ISSN: 1558-1934 ISO Abbreviation: Foot Ankle Clin Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-04 Completed Date: 2010-12-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9615073 Medline TA: Foot Ankle Clin Country: United States |
Other Details:
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Languages: eng Pagination: 411-37 Citation Subset: IM |
Copyright Information:
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2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Orthopaedics, University of Medicine and Dentistry of New Jersey, Newark, 07103, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bone Morphogenetic Proteins
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physiology Bones of Lower Extremity / blood supply, innervation, surgery* Diabetes Complications / physiopathology, surgery*, therapy Electric Stimulation Therapy / methods Fracture Healing / physiology* Humans Orthopedic Procedures / adverse effects, methods* Perioperative Care / adverse effects, methods* Platelet-Rich Plasma / physiology Retrospective Studies Wound Healing / physiology* |
| Chemical | |
Reg. No./Substance:
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0/Bone Morphogenetic Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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