| [Bone tissue engineering for bone defect therapy]. | |
| | |
MedLine Citation:
|
PMID: 20821364 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
In critical size bone defects resulting from failed fracture healing or pseudarthrosis surgery is usually required. In this context, autologous bone grafts and callus distraction represent the gold standard, while sometimes even vascularised bone transfer is mandatory including microsurgical techniques. The availability of donor sites for such procedures is limited and the resulting morbidity significant. Therefore, synthetic bone grafts have been developed as an alternative. They consist of a broad range of different materials such as natural and synthetic polymers, ceramic and compound materials, aiming to mimic the three-dimensional character of autografts. In addition, they may act as a delivery vehicle for growth factors, antibiotics or cells. Their main limitation has been the lack of an intrinsic blood supply, limiting the potential for transplantation. This review provides an overview of matrices, cells and other therapeutic substances in the field of bone tissue engineering. |
| | |
Authors:
|
A M Boos; A Arkudas; U Kneser; R E Horch; J P Beier |
Related Documents
:
|
20665654 - Cyclosporine-impregnated allograft bone sterilized with low-temperature plasma. 18253814 - Bone regeneration using an injectable calcium phosphate/autologous iliac crest bone com... 19531334 - Tissue engineering scaffolds for the regeneration of craniofacial bone. 16857254 - Freeze casting of hydroxyapatite scaffolds for bone tissue engineering. 6473754 - The importance of inconsistent bones. 2401544 - Clinical experience with a new artificial bone graft: preliminary results of a prospect... |
Publication Detail:
|
Type: English Abstract; Journal Article Date: 2010-09-06 |
Journal Detail:
|
Title: Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deutschen Plastischen Chirurgen Volume: 42 ISSN: 1439-3980 ISO Abbreviation: Handchir Mikrochir Plast Chir Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-12-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8302815 Medline TA: Handchir Mikrochir Plast Chir Country: Germany |
Other Details:
|
Languages: ger Pagination: 360-8 Citation Subset: IM |
Copyright Information:
|
© Georg Thieme Verlag KG Stuttgart · New York. |
Affiliation:
|
Universitätsklinikum Erlangen, Plastisch- und Handchirurgische Klinik, Krankenhausstraße 12, Erlangen. anja.boos@uk-erlangen.de |
Vernacular Title:
|
Knochen Tissue Engineering zur Therapie von Knochendefekten. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Endoscopic retrograde cholangiopancreatography.
Next Document: [Significance of abdominal wall CT-angiography in planning DIEA perforator flaps, TRAM flaps and SIE...