Document Detail

Bone density in peripubertal boys with autism spectrum disorders.
MedLine Citation:
PMID:  23124396     Owner:  NLM     Status:  MEDLINE    
We determined whether bone mineral density (BMD) is lower in boys with autism spectrum disorders (ASD) than controls, and also assessed variables that may affect BMD in ASD. BMD was measured using dual energy X-ray absorptiometry (DXA) in 18 boys with ASD and 19 controls 8-14 years old. Boys with ASD had lower BMD Z-scores at the spine, hip and femoral neck, and differences at the hip and femoral neck persisted after controlling for maturity and BMI. Vitamin D intake from food and in serum were lower in ASD subjects, as was exercise activity. We conclude that BMD is lower in peripubertal boys with ASD and may be associated with impaired vitamin D status and lower exercise activity.
Ann M Neumeyer; Amy Gates; Christine Ferrone; Hang Lee; Madhusmita Misra
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of autism and developmental disorders     Volume:  43     ISSN:  1573-3432     ISO Abbreviation:  J Autism Dev Disord     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-14     Completed Date:  2013-10-17     Revised Date:  2014-04-08    
Medline Journal Info:
Nlm Unique ID:  7904301     Medline TA:  J Autism Dev Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1623-9     Citation Subset:  IM    
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MeSH Terms
Absorptiometry, Photon
Age Determination by Skeleton
Body Mass Index
Bone Density / physiology*
Child Development Disorders, Pervasive / physiopathology*
Exercise / physiology
Puberty / physiology*
Reference Values
Risk Factors
Vitamin D / administration & dosage,  blood
Grant Support
1 UL1 RR025758-01/RR/NCRR NIH HHS; UA3 MC 11054//PHS HHS
Reg. No./Substance:
1406-16-2/Vitamin D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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