Document Detail


Bone Architecture and Strength in the Growing Skeleton: The Role of Sedentary Time.
MedLine Citation:
PMID:  24983338     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: Today's youth spend close to sixty percent of their waking hours in sedentary activities; however, we know little about the potentially deleterious effects of sedentary time on bone health during this key period of growth and development. Thus, our objective was to determine if sedentary time is associated with bone architecture, mineral density and strength in children, adolescents and young adults.
METHODS: We used high-resolution peripheral quantitative computed tomography (HR-pQCT, Scanco Medical) to measure bone architecture (trabecular and cortical microstructure, bone macrostructure) and cortical and total bone mineral density (BMD) at the distal tibia (8% site) in 154 males and 174 females (9-20 years) who were participants in the UBC Healthy Bones III Study. We applied finite element analysis to HR-pQCT scans to estimate bone strength. We assessed self-reported screen time in all participants using a questionnaire and sedentary time (volume and patterns) in a subsample of participants with valid accelerometry data (89 males, 117 females; ActiGraph GT1M). We fit sex-specific univariate multivariable regression models controlling for muscle cross-sectional area (MCSA), limb length, maturity, ethnicity, dietary calcium and physical activity.
RESULTS: We did not observe an independent effect of screen time on bone architecture, BMD or strength in either sex (p>0.05). Likewise, when adjusted for MCSA, limb length, maturity, ethnicity, dietary calcium and physical activity, accelerometry-derived volume of sedentary time and breaks in bouts of sedentary time were not a determinant of bone architecture, BMD or strength in either sex (p>0.05).
CONCLUSIONS: Further study is warranted to determine if the lack of an association between sedentary time and bone architecture, BMD and strength at the distal tibia is also present at other skeletal sites.
Authors:
Leigh Gabel; Heather A McKay; Lindsay Nettlefold; Douglas Race; Heather M Macdonald
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-30
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  -     ISSN:  1530-0315     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-7-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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