Document Detail


Bombesin produces hypothermia in hypophysectomized rats.
MedLine Citation:
PMID:  6855453     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intracerebroventricular administration of bombesin, a naturally-occurring peptide, produces hypothermia in the rat. To determine whether a pituitary-dependent step is necessary for this effect, the thermoregulatory response was followed in hypophysectomized and intact rats maintained at room temperature. Significant hypothermia was produced in both experimental groups. This study supports an extra-pituitary mechanism for bombesin-induced hypothermia.
Authors:
F E Rasler
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Life sciences     Volume:  32     ISSN:  0024-3205     ISO Abbreviation:  Life Sci.     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0375521     Medline TA:  Life Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2503-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Body Temperature / drug effects*
Bombesin / administration & dosage,  pharmacology*
Cerebral Ventricles
Hypophysectomy*
Kinetics
Male
Peptides / pharmacology*
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
0/Peptides; 31362-50-2/Bombesin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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