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Bombay blood type and use of red cell apheresis during pregnancy.
MedLine Citation:
PMID:  21252790     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: : Bombay blood type is among the rarest in the world and is associated with anti-H antibodies. These antibodies cause severe hemolysis when exposed to any blood product except Bombay and have been reported to cause hemolytic disease of the newborn.
CASE: : A primigravid woman with Bombay blood type received erythropoietin and underwent autologous blood donation using red cell apheresis. Maternal anti-H immunoglobulin G antibodies were identified and serial evaluation of the middle cerebral artery peak systolic velocity was used to monitor for fetal anemia. Hemolytic disease of the newborn did not develop.
CONCLUSION: : Red cell apheresis is a valuable procedure that results in two units of red blood cells per donation and was well tolerated during pregnancy.
Authors:
Nicole Sprawka; Carolyn Young; Barbara O'brien
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  117     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  463-5     Citation Subset:  AIM; IM    
Affiliation:
From the Division of Maternal Fetal Medicine, Warren Alpert Medical School at Brown University, Providence, Rhode Island; and the Rhode Island Blood Center, Providence, Rhode Island.
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