| Body-weight distribution on forelimbs in rat tail-suspension model. | |
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MedLine Citation:
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PMID: 20803996 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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To understand the tail-suspension model to simulate weightlessness better, this study was to investigate the relationship of the amount of body weight supported by forelimbs between the tilt angles of rat in the model. Normal rat had at least two basic postures. One was standing or walking, in which the forelimbs bear 44.6% of the body weight; the other one was resting, in which 23.9% of body weight was placed on the forelimbs. As for tail-suspended rat, body-weight distribution on forelimbs was linearly related to tilt angle. The linear relationship was y = -0.7423x + 70.849, R2 = 0.9269. The tilt angle should be approximately 35 degrees if normal standing load of 44.6% body weight was placed on the forelimbs. On the other hand, it should be approximately 63 degrees if normal resting load of 23.9% of body weight was placed on forelimbs. Furthermore, the body load on forelimbs in tail-suspension model became much larger if the period of different postures was considered. Therefore, it should be careful if forelimbs are used to be as convenient internal control in tail-suspended rats. |
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Authors:
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Lian-Wen Sun; Chao Wang; Tian Xie; Fang Pu; Yao Sun; Yu-Bo Fan |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine Volume: 44 ISSN: 0233-528X ISO Abbreviation: Aviakosm Ekolog Med Publication Date: 2010 Jan-Feb |
Date Detail:
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Created Date: 2010-08-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9305904 Medline TA: Aviakosm Ekolog Med Country: Russia (Federation) |
Other Details:
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Languages: eng Pagination: 37-9 Citation Subset: IM; S |
Affiliation:
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School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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