Document Detail

Body mass index and serum lipid profile influence serum prostate-specific antigen in Chinese men younger than 50 years of age.
MedLine Citation:
PMID:  21170076     Owner:  NLM     Status:  MEDLINE    
This study is to assess the potential factors that could affect the serum prostate-specific antigen (PSA) level in healthy younger men. We evaluated the associations of age, body mass index (BMI) and serum lipid profile with serum PSA level in 6774 Chinese men (aged 20-49 years) who received a routine health examination. Eligible men were classified into 10-year age groups. BMI was categorized as underweight (<18.5), normal (18.5-22.9), overweight (23.0-24.9), obese (25.0-29.9) and very obese (>30) according to the redefined World Health Organization (WHO) criteria for the Asia-Pacific region. PSA levels were compared among groups as well. In multiple linear regression analysis, PSA was positively correlated with age (P<0.0001). Negative correlations existed between PSA and BMI (P<0.0001) and triglyceride level (P=0.01). No relationship could be found between PSA and serum cholesterol (P=0.711) or high-density lipoprotein (HDL; P =0.665). In addition, we found that serum PSA levels increased with age and decreased with BMI. Our study demonstrates that age, BMI and triglyceride levels influence the PSA level in men <50 years of age.
Ming Liu; Jian-Ye Wang; Ling Zhu; Gang Wan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-12-20
Journal Detail:
Title:  Asian journal of andrology     Volume:  13     ISSN:  1745-7262     ISO Abbreviation:  Asian J. Androl.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-04     Completed Date:  2011-10-27     Revised Date:  2013-09-17    
Medline Journal Info:
Nlm Unique ID:  100942132     Medline TA:  Asian J Androl     Country:  China    
Other Details:
Languages:  eng     Pagination:  640-3     Citation Subset:  IM    
Department of Urology, Beijing Hospital, No. 1 Dahua Road, Dongcheng District, Beijing 100730, China.
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MeSH Terms
Asian Continental Ancestry Group
Body Mass Index*
Lipids / blood*
Middle Aged
Obesity / blood
Overweight / blood
Prostate-Specific Antigen / blood*
Regression Analysis
Retrospective Studies
Thinness / blood
Triglycerides / blood
Reg. No./Substance:
0/Lipids; 0/Triglycerides; EC Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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