Document Detail

Body mass index and prevalence of obesity in a French cohort of patients with schizophrenia.
MedLine Citation:
PMID:  18582344     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the distributions of body mass index in a large sample of patients with schizophrenia, and to examine the association between body weight and antipsychotic drugs. METHOD: The data source was baseline data from a national survey conducted in 2005-2006 in 5756 patients. RESULTS: The mean age of the patients was 37.1 +/- 11.8 years, and the mean BMI was 25.5 +/- 5.2 kg/m(2). In the final logistic regression model, the prevalence of obesity was significantly higher in female patients, age 40-59 vs. 18-29 years, patients in sheltered employment (vs. no income), out-patients (vs. full-time in-patients) and patients treated with concomitant antidepressant. There was a higher rate of obesity, relative to an absence of antipsychotics at entry, for patients receiving the following individual drugs: clozapine, olanzapine, risperidone and amisulpride. CONCLUSION: In patients treated with atypical antipsychotics, we found a significantly higher prevalence of obesity than in those not treated with any antipsychotic medication.
F Limosin; I Gasquet; D Leguay; J-M Azorin; F Rouillon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta psychiatrica Scandinavica     Volume:  118     ISSN:  1600-0447     ISO Abbreviation:  Acta Psychiatr Scand     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-27     Completed Date:  2008-09-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370364     Medline TA:  Acta Psychiatr Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  19-25     Citation Subset:  IM    
Department of Psychiatry, University of Reims, Reims, France.
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MeSH Terms
Ambulatory Care / statistics & numerical data
Antidepressive Agents / adverse effects,  therapeutic use
Antipsychotic Agents / adverse effects,  therapeutic use
Body Mass Index*
Body Weight / drug effects
Cohort Studies
Cross-Sectional Studies
Drug Therapy, Combination
Middle Aged
Obesity / chemically induced,  epidemiology*
Overweight / chemically induced,  epidemiology*
Risk Factors
Schizophrenia / drug therapy,  epidemiology*
Sex Factors
Sheltered Workshops / statistics & numerical data
Reg. No./Substance:
0/Antidepressive Agents; 0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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