Document Detail

Body mass index and physical activity in relation to asthma and atopic diseases in young adults.
MedLine Citation:
PMID:  16503404     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Obesity has been shown to increase the risk of asthma and wheezing. Conditioning exercise might decrease the asthma risk, and that could partly explain the association. The relation between obesity and allergic diseases is quite conflicting. METHODS: The association between body mass index (BMI) and physician-diagnosed asthma, allergic rhinitis or conjunctivitis, atopic dermatitis, and self-reported wheezing was investigated in a questionnaire study among 10,667 Finnish first-year university students aged 18-25 years. Logistic regression was used to evaluate possible confounding by parental education, passive smoking at age 0-2, childhood residential environment, current and past smoking and leisure time physical activity index. RESULTS: In men, there was a greater risk of asthma, but not wheezing with increasing BMI. Compared to those with BMI below 20, OR for male asthma was 1.98 (95% CI 1.11-3.52) in BMI category 20.0-22.4, 1.90 (95% CI 1.05-3.41) in BMI 22.5-24.9, and 3.5 (95% CI 1.63-7.64) in BMI > or = 27.5. Among women, the risks of asthma and wheezing were about two-fold among the overweight-obese subjects. Moderate leisure time physical activity was associated with lower risk of asthma in men (OR 0.62, 95% CI 0.62 (0.42-0.92), but not among women. The risk of allergic rhinoconjunctivitis and atopic dermatitis increased quite linearly with BMI among women but not men. CONCLUSIONS: Low leisure time physical activity seems not to explain the greater risk of asthma among obese men and women. The quite linear association between BMI and both allergic rhinoconjunctivitis and wheezing among women suggests the independent effect of body fat on atopic diseases.
Maritta Kilpeläinen; Erkki O Terho; Hans Helenius; Markku Koskenvuo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-02-28
Journal Detail:
Title:  Respiratory medicine     Volume:  100     ISSN:  0954-6111     ISO Abbreviation:  Respir Med     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-07-31     Completed Date:  2007-06-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908438     Medline TA:  Respir Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1518-25     Citation Subset:  IM    
Department of Pulmonary Diseases and Clinical Allergology, Turku University Hospital, Kiinamyllynkatu 4-8, FIN-20520 Turku, Finland.
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MeSH Terms
Asthma / epidemiology*
Body Mass Index*
Conjunctivitis, Allergic / epidemiology
Dermatitis, Atopic / epidemiology
Finland / epidemiology
Hypersensitivity, Immediate / epidemiology
Motor Activity*
Obesity / epidemiology
Respiratory Sounds*
Rhinitis, Allergic, Perennial / epidemiology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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