Document Detail


Body fat and blood lipids in postmenopausal women are related to resting autonomic nervous system activity.
MedLine Citation:
PMID:  16779552     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study investigated the activity of the autonomic nervous system (ANS), a major influence in normal physiological function, and its association with unfavorable postmenopausal states in body composition, lipid and/or glucose metabolism, or cardiovascular profiles. Body composition, blood pressure, and blood profiles of lipid and glucose of 175 postmenopausal women were measured. Resting ANS activity was assessed by heart rate variability (HRV) power spectral analysis. To scrutinize the influence of ANS activity levels on postmenopausal obesity-related factors, we divided the subjects into a low group ( < 220 ms(2)) and a high group ( > 220 ms(2)), based on the total power of HRV. Low-frequency (P < 0.01) and high-frequency power (P < 0.01) were both significantly lower in the low group. No significant difference was found in age, age at menopause, or years after menopause between the two groups. In contrast, body mass index (P < 0.05), percentages of body fat (P < 0.01), and systolic (P < 0.01) and diastolic (P < 0.01) blood pressure were significantly greater in the low group. As to blood lipid profiles, triglycerides (P < 0.05), total cholesterol (P < 0.05), and low-density lipoprotein cholesterol (P < 0.05) were significantly higher in the low group. Our findings indicate that reduced sympatho-vagal activity is associated with higher postmenopausal body fat content, blood pressure, and blood lipid concentrations. This study further implies that such autonomic depression could be a crucial risk factor in undermining the health and, ultimately, the quality of life, of postmenopausal women.
Authors:
Tetsuya Kimura; Tamaki Matsumoto; Mihoko Akiyoshi; Yoko Owa; Naoyuki Miyasaka; Takeshi Aso; Toshio Moritani
Publication Detail:
Type:  Journal Article     Date:  2006-06-09
Journal Detail:
Title:  European journal of applied physiology     Volume:  97     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-06     Completed Date:  2006-09-26     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  542-7     Citation Subset:  IM    
Affiliation:
Laboratory of Applied Physiology, Graduate School of Human and Environmental Studies, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
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MeSH Terms
Descriptor/Qualifier:
Autonomic Nervous System / physiology*
Blood Pressure / physiology
Body Composition / physiology*
Body Fat Distribution
Cardiovascular Physiological Phenomena
Female
Glucose / metabolism
Heart Rate / physiology
Humans
Lipids / blood*
Middle Aged
Obesity / prevention & control
Postmenopause / metabolism*
Quality of Life
Risk Factors
Chemical
Reg. No./Substance:
0/Lipids; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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