| Body composition in a rat model of moderate uremia. | |
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MedLine Citation:
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PMID: 7341537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To evaluate whether abnormal body composition in uremia is a consequence of undernutrition from poor food intake, body fluid compartments and individual organs were measured in moderately uremic (5/6th nephrectomy) and pair fed control rats and in a second group of moderately uremic and control rats on two levels of dietary protein: 43% (HP) and 18.5% (LP). Uremic rats in both groups had significantly increased total body water (TBW) and extracellular water (ECW) and decreased total body solids (TBS). Heart weight in uremic rats was significantly increased, whereas weight of muscle, brain, adrenal, and fat free liver, as a percent of body weight, did not differ from control rats. There were no differences between uremic rats on HP and LP diets in TBW, ECW, TBS or in heart weight and muscle weight. Uremic rats on HP had increased kidney and liver weights. These data demonstrate abnormal body composition in a rat model of moderate uremia. Changes observed appear to be primarily a consequence of uremia per se rather than of undernutrition or level of dietary protein. |
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Authors:
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R D Adelman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The International journal of pediatric nephrology Volume: 2 ISSN: 0391-6510 ISO Abbreviation: Int J Pediatr Nephrol Publication Date: 1981 Jun |
Date Detail:
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Created Date: 1982-07-08 Completed Date: 1982-07-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8007162 Medline TA: Int J Pediatr Nephrol Country: ITALY |
Other Details:
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Languages: eng Pagination: 79-84 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Composition* Body Water / metabolism Body Weight Dietary Proteins / administration & dosage Disease Models, Animal Male Nutrition Disorders / metabolism Organ Size Rats Rats, Inbred Strains Uremia / metabolism*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Dietary Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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