Document Detail

Blunted nocturnal decline in blood pressure.
MedLine Citation:
PMID:  15470290     Owner:  NLM     Status:  MEDLINE    
Blood pressure normally declines 10%-20% from daytime to sleep. Patients with less than a 10% reduction in daytime blood pressure are referred to as nondippers. A blunted nocturnal decline in blood pressure may be due to diminished sodium excretory capacity, alteration in the autonomic nervous system, or other factors. Secondary hypertension should be considered as a possibility. Target organ damage appears to be more common in nondippers, however, poor reproducibility of nondipping status raises the question as to the appropriate duration of monitoring to establish a diagnosis. Nondippers tend to have a greater reduction in nocturnal blood pressure with nonpharmacologic and pharmacologic treatment.
L Michael Prisant
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of clinical hypertension (Greenwich, Conn.)     Volume:  6     ISSN:  1524-6175     ISO Abbreviation:  J Clin Hypertens (Greenwich)     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-10-07     Completed Date:  2005-01-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100888554     Medline TA:  J Clin Hypertens (Greenwich)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  594-7     Citation Subset:  IM    
Department of Hypertension and Clinical Pharmacology, Medical College of Georgia, Augusta, GA 30912, USA.
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MeSH Terms
Blood Pressure
Circadian Rhythm
Hypertension / physiopathology*

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