Document Detail

Bloody nipple discharge during pregnancy: a rationale for conservative treatment.
MedLine Citation:
PMID:  2325421     Owner:  NLM     Status:  MEDLINE    
Five cases of bloody nipple discharge during pregnancy without associated breast masses were seen over the past 3 years by the author. Because of the reported association of breast cancer with bloody nipple discharge, close follow-up of these women at monthly intervals during pregnancy and trimonthly during the postpartum period was carried out. In all instances, the discharge appeared late during the second trimester or during the third trimester of pregnancy. It was unilateral and spontaneous and arose from multiple ducts, and it was associated with an increase in breast size and always with the larger breast of the two. The discharge cytologic study done on all cases was negative for neoplastic cells and the discharges resolved spontaneously within 2 months of onset. Postpartum follow-up ranging from 6 months to 3 years has revealed no evidence of neoplastic changes thus far. Mammograms ordered before these patients were referred were not helpful due to the increase in density of the breast tissue secondary to the pregnancy. Because a few cases of breast cancer during pregnancy have presented solely with a bloody nipple discharge, I recommend extremely close follow-up of these women and no surgical intervention unless a mass is discovered or the nipple discharge cytology is either suspicious or positive at the initial visit or during follow-up.
R Lafreniere
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of surgical oncology     Volume:  43     ISSN:  0022-4790     ISO Abbreviation:  J Surg Oncol     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-05-16     Completed Date:  1990-05-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0222643     Medline TA:  J Surg Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  228-30     Citation Subset:  IM    
Department of Surgery, University of Calgary, Alberta, Canada.
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MeSH Terms
Breast Diseases / therapy*
Breast Neoplasms / prevention & control
Follow-Up Studies
Nipples / secretion
Pregnancy Complications / therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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