| Blood volume modeling and refilling rate estimation in hemodialysis by continuous hemoglobin monitoring. | |
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MedLine Citation:
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PMID: 8582767 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Eleven bicarbonate hemodialyses (HD) of 6 patients under constant ultrafiltration were continuously monitored with an optical Hb-meter, considered to be a marker of blood volume (BV) changes. A theoretical model was fed experimental data for prediction of blood volume and estimation of vascular parameters, and a time course of rate of refilling was extrapolated. The adequacy of the model was very good for the time course of BV prediction (r2 = 0.85-0.95, n = 11) and for plasma protein concentration (r2 = 0.83-0.86, n = 2). Parameters estimated included (mean-DS): filtration coefficient (Cf) = 0.22 (0.16) dl/min*mmHg, transcapillary hydrostatic pressure (DP) = 17.80 (3.44) mmHg and protein concentration of the refilling fluid (Cref) = 0.45 (0.30) g/dl. In conclusion our study has shown that the model chosen fits the observed BV profile well in all cases, thus the Hb data series can be used for BV dynamic modeling and for estimation of vascular parameters. |
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Authors:
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G Arrigo; R Bucci; G Colasanti; A Rustici; M Sivo; V Rizza; G D'Amico |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The International journal of artificial organs Volume: 18 ISSN: 0391-3988 ISO Abbreviation: Int J Artif Organs Publication Date: 1995 Sep |
Date Detail:
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Created Date: 1996-03-21 Completed Date: 1996-03-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: ITALY |
Other Details:
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Languages: eng Pagination: 509-12 Citation Subset: IM |
Affiliation:
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Division of Nephrology and Dialysis, Ospedale San Carlo Borromeo, Milano, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Proteins / analysis Blood Volume / physiology* Capillary Permeability / physiology Female Hemoglobins / analysis, metabolism* Humans Hypotension / etiology, physiopathology Male Middle Aged Models, Theoretical Monitoring, Physiologic Renal Dialysis / adverse effects, standards* |
| Chemical | |
Reg. No./Substance:
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0/Blood Proteins; 0/Hemoglobins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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