Document Detail

Blood volume and the carotid baroreceptor reflex in conscious rabbits.
MedLine Citation:
PMID:  7318319     Owner:  NLM     Status:  MEDLINE    
1. The effects of acute blood volume change in conscious rabbits on a.c. gain of the carotid baroreceptor reflex with respect to heart rate, blood pressure, cardiac output and systemic vascular resistance were studied. 2. With acute, isohaemic increase in blood volume by 20% and 40% the only consistent trend was a decrease in gain for systemic vascular resistance. 3. With acute reduction in blood volume there was a consistent tendency for gain for heart rate to fall. With 20% reduction in blood volume, gain for cardiac output fell but gain for systemic vascular resistance rose and its phage-lag became shorter, so that gain for blood pressure was unaltered. The enhanced gain for systemic vascular resistance was not sustained with 35% reduction in blood volume, so that gain for blood pressure fell. 4. Thus control of blood pressure by the carotid sinus reflex is remarkably unaffected by acute change in blood volume, and is impaired only when there is depression of gain for cardiac output without a concomitant rise in gain for systemic vascular resistance.
J Ludbrook; I B Faris; G G Jamieson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical science (London, England : 1979)     Volume:  61 Suppl 7     ISSN:  0143-5221     ISO Abbreviation:  Clin. Sci.     Publication Date:  1981 Dec 
Date Detail:
Created Date:  1982-03-26     Completed Date:  1982-03-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7905731     Medline TA:  Clin Sci (Lond)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  173s-175s     Citation Subset:  IM    
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MeSH Terms
Blood Pressure*
Carotid Body / physiology
Pressoreceptors / physiology*
Reflex / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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