Document Detail


Blood, urine, and hair kinetic analysis following an acute lead intoxication.
MedLine Citation:
PMID:  21219705     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of lead exposure resulting from the accidental ingestion of a lead-containing solution is reported. Because of clinical management rapidly performed through chelation therapy by 2,3-dimercaptopropane sulfonate sodium and meso-2,3-dimercaptosuccinic acid, blood lead levels of this 51-year-old patient were moderate (412.9 μg/L) and no clinical symptoms were observed. Numerous blood and urine samples were collected for kinetic analysis of lead elimination. However, we report the first case in which hair samples were analyzed to determine the excretion level of lead after acute intoxication.
Authors:
G Ho; A Keutgens; R Schoofs; S Kotolenko; R Denooz; C Charlier
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of analytical toxicology     Volume:  35     ISSN:  1945-2403     ISO Abbreviation:  J Anal Toxicol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-11     Completed Date:  2011-04-18     Revised Date:  2011-05-10    
Medline Journal Info:
Nlm Unique ID:  7705085     Medline TA:  J Anal Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  60-4     Citation Subset:  IM    
Affiliation:
Service de Toxicologie Clinique, Médicolégale, Environnementale et en Entreprise, Centre Interfacultaire de Recherche du Médicament, ULg, Centre Hospitalier Universitaire Sart-Tilman B35, B-4000 Liège, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Chelating Agents / therapeutic use
Chelation Therapy / methods
Female
Hair / chemistry*
Humans
Kinetics
Lead / blood*,  urine*
Lead Poisoning / diagnosis
Middle Aged
Succimer / therapeutic use*
Unithiol / therapeutic use*
Chemical
Reg. No./Substance:
0/Chelating Agents; 304-55-2/Succimer; 4076-02-2/Unithiol; 7439-92-1/Lead

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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