Document Detail


Blood tritium level as a conservative estimate of soft tissue dose after tritium injection in mice.
MedLine Citation:
PMID:  9570159     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The usefulness of the determination of the tritium concentration in blood for estimating the average soft tissue dose after tritium intake was tested. Tritiated water and a mixture of tritiated amino acids dissolved in saline solution were separately administered to adult male mice by intraperitoneal injection. The tritium levels in the blood, urine, whole body, spleen, liver, testis, and brain were then determined at various periods. With both types of tritium administration, the results suggested that the accumulated dose in the blood pool gave a conservative estimate of the accumulated dose to the soft tissue.
Authors:
M Saito
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Health physics     Volume:  74     ISSN:  0017-9078     ISO Abbreviation:  Health Phys     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-05-12     Completed Date:  1998-05-12     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  2985093R     Medline TA:  Health Phys     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  561-7     Citation Subset:  IM    
Affiliation:
Research Reactor Institute of Kyoto University, Osaka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / metabolism
Animals
Injections, Intraperitoneal
Male
Mice
Radiometry / methods*
Tissue Distribution
Tritium / blood*,  pharmacokinetics
Water
Chemical
Reg. No./Substance:
0/Amino Acids; 10028-17-8/Tritium; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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