Document Detail

Blood transfusion in marrow graft recipients.
MedLine Citation:
PMID:  1511059     Owner:  NLM     Status:  MEDLINE    
Of 182 consecutive patients undergoing allogeneic bone marrow transplantation (BMT), the relative numbers of those who received red blood cells (RBC), platelets (PLT), and granulocytes were 82%, 96%, and 26%, respectively. The transfused patients received an average of 1.26 (SD +/- 2.0) RBC units, 9.41 (SD +/- 13.2) PLT transfusions, and 0.33 (SD +/- 1.1) granulocyte concentrates per week per 50 kg body wt. in the period starting on the day of bone marrow transplantation (BMT) up to 60 days post BMT. The total number of units per transfused patient was 7.7 (range 1-63) RBC, 55.2 (range 2-394) PLT and 6.2 (range 1-36) granulocytes in the same period. Patients with grades II-IV acute graft-versus-host disease (GVHD) needed more RBC and PLT (p less than 0.001) than patients with grades 0-I acute GVHD. Patients with late engraftment required more granulocyte and PLT transfusion than those with early engraftment (p less than 0.05). Patients with high-risk malignancy had greater need for RBC and PLT than "low-risk patients" (p less than 0.02 and p less than 0.01), respectively). Patients with major ABO-incompatible donors showed a greater need for RBC than patients with minor ABO incompatibility (p = 0.02) or ABO identical donors (p = 0.01). Patients with relatively poor estimated survival required the most RBC and PLT.
P Pihlstedt; T Paulin; B Sundberg; B Nilsson; O Ringdén
Related Documents :
7973909 - Thrombotic thrombocytopenic purpura associated with sickle cell-hemoglobin c disease.
8122949 - Acute chest syndrome in adult afro-caribbean patients with sickle cell disease. analysi...
3002959 - Heterogeneity of haplotypes among patients with severe cooley disease in eastern sicily.
7534399 - Fetal haemoglobin variations following hydroxyurea treatment in patients with cyanotic ...
106639 - Radiographic changes of the skull in sickle cell anemia.
16997049 - The epidemiology of hemoglobin levels in patients with type 2 diabetes.
715039 - Loss of silicone implants after subcutaneous mastectomy and reconstruction.
10680669 - Nationwide epidemiological survey of chronic pancreatitis in japan.
11305749 - Magnetic resonance imaging and 1h-magnetic resonance spectroscopy in amyotrophic latera...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of hematology     Volume:  65     ISSN:  0939-5555     ISO Abbreviation:  Ann. Hematol.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-09-28     Completed Date:  1992-09-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9107334     Medline TA:  Ann Hematol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  66-70     Citation Subset:  IM    
Blood Bank, Karolinska Hospital, Stockholm, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
ABO Blood-Group System
Blood Component Transfusion
Blood Group Incompatibility
Blood Grouping and Crossmatching
Blood Transfusion*
Bone Marrow Transplantation* / mortality
Child, Preschool
Middle Aged
Survival Rate
Reg. No./Substance:
0/ABO Blood-Group System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Elliptocytosis associated with an abnormal alpha glycophorin.
Next Document:  Maintenance with low-dose cytarabine for acute myeloid leukemia in complete remission.