| Blood responses to titanium surface with TiO(2) nano-mesh structure. | |
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MedLine Citation:
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PMID: 21457350 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objectives: The goal of this study was to enhance the blood responses to titanium (Ti) surfaces used for dental implant application through the formation of a TiO(2) nano-mesh surface layer produced by a fast electrochemical anodization treatment. Material and methods: Electrochemical anodization treatments with different anodization currents and temperatures in an alkaline solution were used to create a nano-mesh oxide layer on polished Ti surface. Surface characterizations of the mesh structure were carried out using thin-film X-ray diffractometer, field-emission scanning electron microscope, and atomic force microscope. The blood responses, including the blood-clotting ability and platelet adhesion morphology, to the test Ti surfaces were evaluated. The blood-clotting ability, in terms of optical density of blood, was statistically analyzed using a nonparametric method, Kruskal-Wallis test, for the factor of anodization treatment. Results: A multilayer TiO(2) nano-mesh structure was rapidly formed on the polished Ti surface using a simple electrochemical anodization treatment in an alkaline solution. The TiO(2) nano-mesh had an average mesh size between 34 and 93 nm, depending on the anodization current and temperature. The features on the TiO(2) nano-mesh structure on the anodized Ti surface were of a similar size scale as blood proteins, giving the material better blood clot ability (P<0.05) and improved platelet activation and aggregation as compared with an untreated polished Ti surface. Conclusions: The formation of TiO(2) nano-mesh on the Ti surfaces was shown to enhance blood responses, which we expect to promote cell growth in the application of dental implants. To cite this article: Huang H-H, Chen J-Y, Lin M-C, Wang Y-T, Lee T-L, Chen L-K. Blood responses to titanium surface with TiO(2) nano-mesh structure. Clin. Oral Impl. Res. xx, 2011; 000-000. doi: 10.1111/j.1600-0501.2010.02152.x. |
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Authors:
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Her-Hsiung Huang; Jing-Yi Chen; Mau-Chin Lin; Yu-Tsai Wang; Tien-Lin Lee; Li-Kai Chen |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-4 |
Journal Detail:
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Title: Clinical oral implants research Volume: - ISSN: 1600-0501 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105713 Medline TA: Clin Oral Implants Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 John Wiley & Sons A/S. |
Affiliation:
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Department of Dentistry, National Yang-Ming University, Taipei, Taiwan Department of Dentistry, Taipei City Hospital, Taipei, Taiwan Taipei Veterans General Hospital, Taipei, Taiwan Department of Dental Laboratory Technology, Min-Hwei College of Health Care Management, Tainan, Taiwan Institute of Stomatology, Chung Shan Medical University, Taichung, Taiwan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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