| Blood pressure variability in patients with diabetes mellitus. | |
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MedLine Citation:
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PMID: 20719784 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Reduced arterial compliance in patients with diabetes mellitus has been shown in several studies, but it has not been significantly associated with either atherosclerosis or vessel wall thickness. Blood pressure variability is still poorly explored in diabetic patients. The aim of this study was to compare blood pressure variability and arterial compliance in patients with type 2 diabetes mellitus and controls matched for sex, age, and weight. Arterial compliance was measured and noninvasive 24-h ambulatory blood pressure monitoring was performed in 18 diabetic patients and 18 controls. There was significantly higher 24-h systolic blood pressure variability (17.7 +/- 6.8 vs. 14.6 +/- 2.6 mm Hg), diastolic blood pressure variability (15.6 +/- 7.1 vs. 11.4 +/- 3.1 mm Hg), and mean arterial blood pressure variability (14.8 +/- 7.0 vs. 11.1 +/- 2.9) in diabetic patients. Systolic, diastolic, and mean arterial blood pressure variability was significantly higher during daytime but not night time in diabetic patients compared to controls. Diabetic patients also had significantly reduced small artery compliance, but no differences in large artery compliance, cardiac output, or systemic vascular resistance. The findings suggest that hyperglycemia may affect the compliance of the vascular system, resulting in high blood pressure fluctuations. |
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Authors:
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Rafidah Hanim Mokhtar; Azizi Ayob; Noriah Mohd Noor |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Asian cardiovascular & thoracic annals Volume: 18 ISSN: 1816-5370 ISO Abbreviation: Asian Cardiovasc Thorac Ann Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-19 Completed Date: 2010-12-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9503417 Medline TA: Asian Cardiovasc Thorac Ann Country: Singapore |
Other Details:
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Languages: eng Pagination: 344-8 Citation Subset: IM |
Affiliation:
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International Islamic University of Malaysia, Bandar Indera Mahkota, Pahang, Malaysia. rafidahhanim@usim.edu.my |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Arteries / physiopathology Blood Glucose / metabolism Blood Pressure* Blood Pressure Monitoring, Ambulatory Case-Control Studies Circadian Rhythm Compliance Cross-Sectional Studies Diabetes Mellitus, Type 2 / blood, complications, physiopathology* Diabetic Angiopathies / blood, etiology, physiopathology* Diastole Female Humans Lipids / blood Malaysia Male Middle Aged Systole Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Lipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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