Document Detail

Blood pressure trend and cardiovascular events in nuns in a secluded order: a 30-year follow-up study.
MedLine Citation:
PMID:  9105646     Owner:  NLM     Status:  MEDLINE    
30-year data are presented on blood pressure and cardiovascular morbidity and mortality for 144 nuns living in a secluded order in six nunnerlie in Umbria, central Italy and 138 lay women from the same region. There were no significant differences at baseline regarding age, blood pressure, body mass index, race, ethnic background, menarche, family history of hypertension or 24-hour urinary sodium excretion. None of the women were smokers and none took birth control pills nor did they use estrogen replacement therapy. During the observation period blood pressure remained remarkably stable among the nuns. None showed a rise in diastolic blood pressure to above 90 mm Hg. On the contrary the lay women showed the expected rise in blood pressure with age. This resulted in a gradually greater difference (delta > 30/15 mm Hg) in blood pressure between the two groups, which was statistically significant. There were 31 fatal and 69 non-fatal cardiovascular events during the 30 years of follow-up. These were significantly more common in the lay women, 10 vs. 21 fatal and 21 vs. 48 non-fatal in the nuns and lay women respectively. It appears reasonable to assume that the difference in psychosocial stress is the main underlying factor for the observed findings.
M Timio; G Lippi; S Venanzi; S Gentili; G Quintaliani; C Verdura; C Monarca; P Saronio; F Timio
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Blood pressure     Volume:  6     ISSN:  0803-7051     ISO Abbreviation:  Blood Press.     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-06-23     Completed Date:  1997-06-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9301454     Medline TA:  Blood Press     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  81-7     Citation Subset:  IM    
Department of Internal Medicine and Nephrology, Hospital of Foligno, Italy.
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MeSH Terms
Blood Pressure*
Cardiovascular Diseases / epidemiology*,  physiopathology
Follow-Up Studies
Life Style*
Longitudinal Studies
Patient Selection
Survival Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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