Document Detail

Blood pressure response to transcendental meditation: a meta-analysis.
MedLine Citation:
PMID:  18311126     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Prior clinical trials suggest that the Transcendental Meditation technique may decrease blood pressure of normotensive and hypertensive individuals but study-quality issues have been raised. This study was designed to assess effects of Transcendental Meditation on blood pressure using objective quality assessments and meta-analyses. METHODS: PubMed and Cochrane databases through December 2006 and collected publications on Transcendental Meditation were searched. Randomized, controlled trials comparing blood pressure responses to the Transcendental Meditation technique with a control group were evaluated. Primary outcome measures were changes in systolic and diastolic blood pressure after practicing Transcendental Meditation or following control procedures. A specific rating system (0-20 points) was used to evaluate studies and random-effects models were used for meta-analyses. RESULTS: Nine randomized, controlled trials met eligibility criteria. Study-quality scores ranged from low (score, 7) to high (16) with three studies of high quality (15 or 16) and three of acceptable quality (11 or 12). The random-effects meta-analysis model for systolic and diastolic blood pressure, respectively, indicated that Transcendental Meditation, compared to control, was associated with the following changes: -4.7 mm Hg (95% confidence interval (CI), -7.4 to -1.9 mm Hg) and -3.2 mm Hg (95% CI, -5.4 to -1.3 mm Hg). Subgroup analyses of hypertensive groups and high-quality studies showed similar reductions. CONCLUSIONS: The regular practice of Transcendental Meditation may have the potential to reduce systolic and diastolic blood pressure by approximately 4.7 and 3.2 mm Hg, respectively. These are clinically meaningful changes.
James W Anderson; Chunxu Liu; Richard J Kryscio
Related Documents :
2889416 - Ibuprofen interferes with the efficacy of antihypertensive drugs. a randomized, double-...
6390696 - Comparison of the effectiveness of a beta blocker (atenolol) and a diuretic (chlorthali...
8613276 - Community-based education classes for hypertension control. a 1.5-year randomized contr...
20670726 - Blood pressure and outcomes in very old hypertensive coronary artery disease patients: ...
625016 - The effects of position and skin temperature on the capillary pressures in the fingers ...
25194156 - Evaluation of a brachial cuff and suprasystolic waveform algorithm method to noninvasiv...
Publication Detail:
Type:  Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't     Date:  2008-01-31
Journal Detail:
Title:  American journal of hypertension     Volume:  21     ISSN:  0895-7061     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-03     Completed Date:  2008-07-01     Revised Date:  2009-02-24    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  310-6     Citation Subset:  IM    
Division of Endocrinology and Molecular Medicine, Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Blood Pressure / physiology*
Hypertension / physiopathology,  psychology*,  therapy
Middle Aged
Quality Assurance, Health Care
Randomized Controlled Trials as Topic
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Altered relationship of blood pressure to adiposity in hypertension.
Next Document:  Biodiversity and biogeography of phages in modern stromatolites and thrombolites.